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The aptamer BT200 blocks von Willebrand factor and platelet function in blood of stroke patients
The effect of conventional anti-platelet agents is limited in secondary stroke prevention, and their effects are blunted under high shear stress in the presence of increased levels of circulating von Willebrand factor (VWF). VWF is critically involved in thrombus formation at sites of stenotic extra...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7862663/ https://ncbi.nlm.nih.gov/pubmed/33542410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82747-7 |
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