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Hepatic Expression of the Serine Palmitoyltransferase Subunit Sptlc2 Reduces Lipid Droplets in the Liver by Activating VLDL Secretion
OBJECTIVE: Ceramide is a signaling molecule that contributes to insulin resistance and hepatosteatosis. In the present study, we activated de novo ceramide synthesis by inducing the hepatic expression of Sptlc2 to investigate the role of ceramide in glucose and lipid metabolism. METHODS: We first co...
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| Publié dans: | J Lipid Atheroscler |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Korean Society of Lipidology and Atherosclerosis
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7379091/ https://ncbi.nlm.nih.gov/pubmed/32821738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12997/jla.2020.9.2.291 |
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