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Functional characterization of the promoter for the mouse SPTLC2 gene, which encodes subunit 2 of serine palmitoyltransferase

A series of luciferase reporter constructs was prepared from a 1035-bp fragment of mouse genomic DNA flanking the 5′ -coding sequence for the SPTLC2 subunit of serine palmitoyltransferase, the initial enzyme of de novo sphingolipid biosynthesis. The full-length DNA fragment promoted strong reporter...

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Detalhes bibliográficos
Main Authors: Linn, Stephen C., Andras, Lindsay M., Kim, Hee-Sook, Wei, Jia, Nagiec, M. Marek, Dickson, Robert C., Merrill, Alfred H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698862/
https://ncbi.nlm.nih.gov/pubmed/17070807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2006.10.025
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