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The SPTLC3 Subunit of Serine Palmitoyltransferase Generates Short Chain Sphingoid Bases
The enzyme serine palmitoyltransferase (SPT) catalyzes the rate-limiting step in the de novo synthesis of sphingolipids. Previously the mammalian SPT was described as a heterodimer composed of two subunits, SPTLC1 and SPTLC2. Recently we identified a novel third SPT subunit (SPTLC3). SPTLC3 shows ab...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785320/ https://ncbi.nlm.nih.gov/pubmed/19648650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023192 |
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