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Hepatic Expression of the Serine Palmitoyltransferase Subunit Sptlc2 Reduces Lipid Droplets in the Liver by Activating VLDL Secretion

OBJECTIVE: Ceramide is a signaling molecule that contributes to insulin resistance and hepatosteatosis. In the present study, we activated de novo ceramide synthesis by inducing the hepatic expression of Sptlc2 to investigate the role of ceramide in glucose and lipid metabolism. METHODS: We first co...

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Bibliografiske detaljer
Udgivet i:J Lipid Atheroscler
Main Authors: Kim, Goon-Tae, Kim, Su-Jung, Park, Si-Hyun, Lee, Dongyup, Park, Tae-Sik
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society of Lipidology and Atherosclerosis 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379091/
https://ncbi.nlm.nih.gov/pubmed/32821738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12997/jla.2020.9.2.291
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