AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

Steroid hormones, including glucocorticoids and androgens, have potent actions to regulate many cellular processes within the liver. The steroid A-ring reductase, 5β-reductase (AKR1D1), is predominantly expressed in the liver, where it inactivates steroid hormones and, in addition, plays a crucial r...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Steroid Biochem Mol Biol
Hlavní autoři: Nikolaou, Nikolaos, Gathercole, Laura L., Kirkwood, Lucy, Dunford, James E., Hughes, Beverly A., Gilligan, Lorna C., Oppermann, Udo, Penning, Trevor M., Arlt, Wiebke, Hodson, Leanne, Tomlinson, Jeremy W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375835/
https://ncbi.nlm.nih.gov/pubmed/30769091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2019.02.002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky