Chargement en cours...

Human and Murine Steroid 5β-Reductases (AKR1D1 and AKR1D4): Insights into the Role of the Catalytic Glutamic Acid

Mammalian steroid 5β-reductases belong to the Aldo-Keto Reductase 1D sub-family and are essential for the formation of A-ring 5β-reduced steroids. Steroid 5β-reduction is required for the biosynthesis of bile-acids and the metabolism of all steroid hormones that contain a Δ(4)-3-ketosteroid function...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Chem Biol Interact
Auteurs principaux: Chen, Mo, Wangtrakuldee, Phumvadee, Zang, Tianzhu, Duan, Ling, Gathercole, Laura L., Tomlinson, Jeremy W., Penning, Trevor M.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500757/
https://ncbi.nlm.nih.gov/pubmed/30928400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.03.025
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!