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5β-Reduced Steroids and Human Δ(4)-3-Ketosteroid 5β-Reductase (AKR1D1)

5β-Reduced steroids are non-planar steroids that have 90° bend in their structure to create an A/B cis-ring junction. This novel property is required for bile-acids to act as emulsifiers, but in addition 5β-reduced steroids have remarkable physiology and may act as potent tocolytic agents, endogenou...

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Détails bibliographiques
Auteurs principaux: Chen, Mo, Penning, Trevor M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971473/
https://ncbi.nlm.nih.gov/pubmed/24513054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2014.01.013
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