Differential activity and expression of human 5β-reductase (AKR1D1) splice variants

Steroid hormones, including glucocorticoids and androgens, exert a wide variety of effects in the body across almost all tissues. The steroid A-ring 5β-reductase (AKR1D1) is expressed in human liver and testes, and three splice variants have been identified (AKR1D1-001, AKR1D1-002, AKR1D1-006). Amon...

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Vydáno v:J Mol Endocrinol
Hlavní autoři: Appanna, Nathan, Gibson, Hylton, Gangitano, Elena, Dempster, Niall J, Morris, Karen, George, Sherly, Arvaniti, Anastasia, Gathercole, Laura L, Keevil, Brian, Penning, Trevor M, Storbeck, Karl-Heinz, Tomlinson, Jeremy W, Nikolaou, Nikolaos
Médium: Artigo
Jazyk:Inglês
Vydáno: Bioscientifica Ltd 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7965358/
https://ncbi.nlm.nih.gov/pubmed/33502336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-20-0160
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