טוען...
cFLIP(L) protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
Cell death and inflammation are interdependent host responses to infection. During pyroptotic cell death, interleukin-1β (IL-1β) release occurs through caspase-1 and caspase-11–mediated gasdermin D pore formation. In vivo, responses to lipopolysaccharide (LPS) result in IL-1β secretion. In vitro, ho...
שמור ב:
| הוצא לאור ב: | Science |
|---|---|
| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7375259/ https://ncbi.nlm.nih.gov/pubmed/32193329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay3878 |
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