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FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP

cFLIP (cellular FLICE-like inhibitory protein) is structurally related to caspase-8 but lacks proteolytic activity due to multiple amino acid substitutions of catalytically important residues. cFLIP protein is evolutionarily conserved and expressed as three functionally different isoforms in humans...

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Foilsithe in:Int J Mol Sci
Main Authors: Tsuchiya, Yuichi, Nakabayashi, Osamu, Nakano, Hiroyasu
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691174/
https://ncbi.nlm.nih.gov/pubmed/26694384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226232
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