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FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP
cFLIP (cellular FLICE-like inhibitory protein) is structurally related to caspase-8 but lacks proteolytic activity due to multiple amino acid substitutions of catalytically important residues. cFLIP protein is evolutionarily conserved and expressed as three functionally different isoforms in humans...
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| Publicado en: | Int J Mol Sci |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4691174/ https://ncbi.nlm.nih.gov/pubmed/26694384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226232 |
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