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Mind bomb 1 regulation of cFLIP interactions
Mind bomb 1 (Mib1) is a multidomain E3 ligase that directs ubiquitination of the Notch ligands Delta and Jagged to promote their endocytosis. Here we examine Notch-independent functions of Mib1 and find that its activities are linked to the initiation of the extrinsic cell death pathway. Expression...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777394/ https://ncbi.nlm.nih.gov/pubmed/19710364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00214.2009 |
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