Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFα-induced apoptosis

The linear ubiquitin chain assembly complex (LUBAC) regulates NF-κB activation by modifying proteins with linear (M1-linked) ubiquitination chains. Although LUBAC also regulates the apoptosis pathway, the precise mechanism by which LUBAC regulates apoptosis remains not fully defined. Here, we report...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tang, Yong, Joo, Donghyun, Liu, Guangna, Tu, Hailin, You, Jeffrey, Jin, Jianping, Zhao, Xueqiang, Hung, Mien-Chie, Lin, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311529/
https://ncbi.nlm.nih.gov/pubmed/30361438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005449
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados