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Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFα-induced apoptosis
The linear ubiquitin chain assembly complex (LUBAC) regulates NF-κB activation by modifying proteins with linear (M1-linked) ubiquitination chains. Although LUBAC also regulates the apoptosis pathway, the precise mechanism by which LUBAC regulates apoptosis remains not fully defined. Here, we report...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6311529/ https://ncbi.nlm.nih.gov/pubmed/30361438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005449 |
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