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Computational modelling of LY303511 and TRAIL-induced apoptosis suggests dynamic regulation of cFLIP
Motivation: TRAIL has been widely studied for the ability to kill cancer cells selectively, but its clinical usefulness has been hindered by the development of resistance. Multiple compounds have been identified that sensitize cancer cells to TRAIL-induced apoptosis. The drug LY303511 (LY30), combin...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562069/ https://ncbi.nlm.nih.gov/pubmed/23239672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts702 |
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