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Computational modelling of LY303511 and TRAIL-induced apoptosis suggests dynamic regulation of cFLIP
Motivation: TRAIL has been widely studied for the ability to kill cancer cells selectively, but its clinical usefulness has been hindered by the development of resistance. Multiple compounds have been identified that sensitize cancer cells to TRAIL-induced apoptosis. The drug LY303511 (LY30), combin...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562069/ https://ncbi.nlm.nih.gov/pubmed/23239672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts702 |
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