Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation

Withanolide E, a steroidal lactone from Physalis peruviana, was found to be highly active for sensitizing renal carcinoma cells and a number of other human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis. Withanolide E, the most potent and least tox...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Henrich, C J, Brooks, A D, Erickson, K L, Thomas, C L, Bokesch, H R, Tewary, P, Thompson, C R, Pompei, R J, Gustafson, K R, McMahon, J B, Sayers, T J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669816/
https://ncbi.nlm.nih.gov/pubmed/25719250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.38
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