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Down-regulation of cFLIP following reovirus infection sensitizes human ovarian cancer cells to TRAIL-induced apoptosis

Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) shows promise as a chemotherapeutic agent. However, many human cancer cells are resistant to killing by TRAIL. We have previously demonstrated that reovirus infection increases the susceptibility of human lung (H157) and breast (ZR75-1)...

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Bibliografski detalji
Glavni autori: Clarke, P., Tyler, K. L.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365758/
https://ncbi.nlm.nih.gov/pubmed/17136319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-006-0528-4
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