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Inhibition of Methyltransferases Accelerates Degradation of cFLIP and Sensitizes B-Cell Lymphoma Cells to TRAIL-Induced Apoptosis

Non-Hodgkin lymphomas (NHLs) are characterized by specific abnormalities that alter cell cycle regulation, DNA damage response, and apoptotic signaling. It is believed that cancer cells are particularly sensitive to cell death induced by tumor necrosis factor α–related apoptosis-inducing ligand (TRA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Braun, Frank K., Mathur, Rohit, Sehgal, Lalit, Wilkie-Grantham, Rachel, Chandra, Joya, Berkova, Zuzana, Samaniego, Felipe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349737/
https://ncbi.nlm.nih.gov/pubmed/25738497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117994
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