Inhibition of Methyltransferases Accelerates Degradation of cFLIP and Sensitizes B-Cell Lymphoma Cells to TRAIL-Induced Apoptosis

Non-Hodgkin lymphomas (NHLs) are characterized by specific abnormalities that alter cell cycle regulation, DNA damage response, and apoptotic signaling. It is believed that cancer cells are particularly sensitive to cell death induced by tumor necrosis factor α–related apoptosis-inducing ligand (TRA...

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Pubblicato in:PLoS One
Autori principali: Braun, Frank K., Mathur, Rohit, Sehgal, Lalit, Wilkie-Grantham, Rachel, Chandra, Joya, Berkova, Zuzana, Samaniego, Felipe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349737/
https://ncbi.nlm.nih.gov/pubmed/25738497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117994
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