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FAS-antisense 1 lncRNA and production of soluble versus membrane Fas in B-cell lymphoma

Impaired Fas-mediated apoptosis is associated with poor clinical outcomes and cancer chemoresistance. Soluble Fas receptor (sFas), produced by skipping of exon 6, inhibits apoptosis by sequestering Fas ligand. Serum sFas is associated with poor prognosis of non-Hodgkin's lymphomas. We found tha...

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Bibliografiske detaljer
Udgivet i:Leukemia
Main Authors: Sehgal, Lalit, Mathur, Rohit, Braun, Frank K., Wise, Jillian F., Berkova, Zuzana, Neelapu, Sattva, Kwak, Larry W., Samaniego, Felipe
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827933/
https://ncbi.nlm.nih.gov/pubmed/24811343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.126
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