Nucleolin inhibits Fas ligand binding and suppresses Fas-mediated apoptosis in vivo via a surface nucleolin-Fas complex

Resistance to Fas-mediated apoptosis is associated with poor cancer outcomes and chemoresistance. To elucidate potential mechanisms of defective Fas signaling, we screened primary lymphoma cell extracts for Fas-associated proteins that would have the potential to regulate Fas signaling. An activatio...

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Detalhes bibliográficos
Main Authors: Wise, Jillian F., Berkova, Zuzana, Mathur, Rohit, Zhu, Haifeng, Braun, Frank K., Tao, Rong-Hua, Sabichi, Anita L., Ao, Xue, Maeng, Hoyoung, Samaniego, Felipe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674671/
https://ncbi.nlm.nih.gov/pubmed/23599269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-471094
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