CD74 interferes with the expression of fas receptor on the surface of lymphoma cells

BACKGROUND: Resistance to Fas-mediated apoptosis limits the efficacy of currently available chemotherapy regimens. We identified CD74, which is known to be overexpressed in hematological malignancies, as one of the factors interfering with Fas-mediated apoptosis. METHODS: CD74 expression was suppres...

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Hauptverfasser: Berkova, Zuzana, Wang, Shu, Ao, Xue, Wise, Jillian F, Braun, Frank K, Rezaeian, Abdol H, Sehgal, Lalit, Goldenberg, David M, Samaniego, Felipe
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210479/
https://ncbi.nlm.nih.gov/pubmed/25304249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0080-y
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