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Clonal evolution driven by superdriver mutations
BACKGROUND: Tumors are widely recognized to progress through clonal evolution by sequentially acquiring selectively advantageous genetic alterations that significantly contribute to tumorigenesis and thus are termned drivers. Some cancer drivers, such as TP53 point mutation or EGFR copy number gain,...
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| Publicado en: | BMC Evol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7370525/ https://ncbi.nlm.nih.gov/pubmed/32689942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-020-01647-y |
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