טוען...
Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia
In chronic lymphocytic leukemia (CLL), the worst prognosis is associated with TP53 defects with the affected patients being potentially directed to alternative treatment. Therapy administration was shown to drive the selection of new TP53 mutations in CLL. Using ultra-deep next-generation sequencing...
שמור ב:
| הוצא לאור ב: | Leukemia |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4396398/ https://ncbi.nlm.nih.gov/pubmed/25287991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.297 |
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