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Inferring clonal evolution of tumors from single nucleotide somatic mutations
BACKGROUND: High-throughput sequencing allows the detection and quantification of frequencies of somatic single nucleotide variants (SNV) in heterogeneous tumor cell populations. In some cases, the evolutionary history and population frequency of the subclonal lineages of tumor cells present in the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3922638/ https://ncbi.nlm.nih.gov/pubmed/24484323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-35 |
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