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PhyloWGS: Reconstructing subclonal composition and evolution from whole-genome sequencing of tumors
Tumors often contain multiple subpopulations of cancerous cells defined by distinct somatic mutations. We describe a new method, PhyloWGS, which can be applied to whole-genome sequencing data from one or more tumor samples to reconstruct complete genotypes of these subpopulations based on variant al...
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| 出版年: | Genome Biol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359439/ https://ncbi.nlm.nih.gov/pubmed/25786235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0602-8 |
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