A practical guide to cancer subclonal reconstruction from DNA sequencing

Subclonal reconstruction from bulk tumor DNA sequencing has become a pillar of cancer evolution studies, providing insight into the clonality and relative ordering of mutations and mutational processes. We provide an outline of the complex computational approaches used for subclonal reconstruction f...

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Foilsithe in:Nat Methods
Main Authors: Tarabichi, Maxime, Salcedo, Adriana, Deshwar, Amit G., Leathlobhair, Máire Ni, Wintersinger, Jeff, Wedge, David C., Loo, Peter Van, Morris, Quaid D., Boutros, Paul C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2021
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867630/
https://ncbi.nlm.nih.gov/pubmed/33398189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-01013-2
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