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TrackSigFreq: subclonal reconstructions based on mutation signatures and allele frequencies
Mutational signatures are patterns of mutation types, many of which are linked to known mutagenic processes. Signature activity represents the proportion of mutations a signature generates. In cancer, cells may gain advantageous phenotypes through mutation accumulation, causing rapid growth of that...
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| 發表在: | Pac Symp Biocomput |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6905203/ https://ncbi.nlm.nih.gov/pubmed/31797600 |
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