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Revisiting a controversy: The effect of EGF on EGFR dimer stability

EGFR is a receptor tyrosine kinase that plays a critical role in cell proliferation, differentiation, survival and migration. Its activating ligand, EGF, has long been believed to stabilize the EGFR dimer. Two research studies aimed at quantitative measurements of EGFR dimerization, however, have le...

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Vydáno v:Biochim Biophys Acta Biomembr
Hlavní autoři: Singh, Deo R., King, Christopher, Salotto, Matt, Hristova, Kalina
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365603/
https://ncbi.nlm.nih.gov/pubmed/31295474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2019.07.003
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