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Revisiting a controversy: The effect of EGF on EGFR dimer stability

EGFR is a receptor tyrosine kinase that plays a critical role in cell proliferation, differentiation, survival and migration. Its activating ligand, EGF, has long been believed to stabilize the EGFR dimer. Two research studies aimed at quantitative measurements of EGFR dimerization, however, have le...

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Detalles Bibliográficos
Publicado en:Biochim Biophys Acta Biomembr
Main Authors: Singh, Deo R., King, Christopher, Salotto, Matt, Hristova, Kalina
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365603/
https://ncbi.nlm.nih.gov/pubmed/31295474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2019.07.003
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