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Two EGF molecules contribute additively to stabilization of the EGFR dimer.

Receptor dimerization is generally considered to be the primary signaling event upon binding of a growth factor to its receptor at the cell surface. Little, however, is known about the precise molecular details of ligand-induced receptor dimerization, except for studies of the human growth hormone (...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lemmon, M A, Bu, Z, Ladbury, J E, Zhou, M, Pinchasi, D, Lax, I, Engelman, D M, Schlessinger, J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169635/
https://ncbi.nlm.nih.gov/pubmed/9029149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.2.281
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