Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease

Parkinson disease (PD) is a neurodegenerative disorder caused by the progressive loss of midbrain dopaminergic neurons, and mitochondrial dysfunction is involved in its pathogenesis. This study aimed to establish an imaging-based, semi-automatic, high-throughput system for the quantitative detection...

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Publicado en:Stem Cell Reports
Autores principales: Yamaguchi, Akihiro, Ishikawa, Kei-ichi, Inoshita, Tsuyoshi, Shiba-Fukushima, Kahori, Saiki, Shinji, Hatano, Taku, Mori, Akio, Oji, Yutaka, Okuzumi, Ayami, Li, Yuanzhe, Funayama, Manabu, Imai, Yuzuru, Hattori, Nobutaka, Akamatsu, Wado
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355139/
https://ncbi.nlm.nih.gov/pubmed/32470327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.04.011
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