טוען...
Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease
Huntington disease (HD) is caused by an expansion mutation of the N-terminal polyglutamine of huntingtin (mHTT). mHTT is ubiquitously present, but it induces noticeable damage to the brain’s striatum, thereby affecting motor, psychiatric, and cognitive functions. The striatal damage and progression...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7354937/ https://ncbi.nlm.nih.gov/pubmed/32581130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002144117 |
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