Rhes, a striatal-enriched protein, promotes mitophagy via Nix

Elimination of dysfunctional mitochondria via mitophagy is essential for cell survival and neuronal functions. But, how impaired mitophagy participates in tissue-specific vulnerability in the brain remains unclear. Here, we find that striatal-enriched protein, Rhes, is a critical regulator of mitoph...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Sharma, Manish, Ramírez-Jarquín, Uri Nimrod, Rivera, Oscar, Kazantzis, Melissa, Eshraghi, Mehdi, Shahani, Neelam, Sharma, Vishakha, Tapia, Ricardo, Subramaniam, Srinivasa
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876193/
https://ncbi.nlm.nih.gov/pubmed/31676548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912868116
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