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Exaggerated mitophagy: a weapon of striatal destruction in the brain?
Mechanisms responsible for neuronal vulnerability in the brain remain unclear. Striatal neurons are preferentially damaged by 3-nitropropionic acid (3-NP), a mitochondrial complex-II inhibitor, causing striatal damage reminiscent of Huntington's disease (HD), but the mechanisms of the selectivi...
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| Publicado no: | Biochem Soc Trans |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7200642/ https://ncbi.nlm.nih.gov/pubmed/32129826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20191283 |
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