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Rhes, a Striatal-selective Protein Implicated in Huntington Disease, Binds Beclin-1 and Activates Autophagy

The protein mutated in Huntington disease (HD), mutant huntingtin (mHtt), is expressed throughout the brain and body. However, the pathology of HD is characterized by early and dramatic destruction selectively of the striatum. We previously reported that the striatal-specific protein Rhes binds mHtt...

詳細記述

保存先:
書誌詳細
主要な著者: Mealer, Robert G., Murray, Alexandra J., Shahani, Neelam, Subramaniam, Srinivasa, Snyder, Solomon H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916556/
https://ncbi.nlm.nih.gov/pubmed/24324270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536912
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