Llwytho...

Rhes, a Striatal-selective Protein Implicated in Huntington Disease, Binds Beclin-1 and Activates Autophagy

The protein mutated in Huntington disease (HD), mutant huntingtin (mHtt), is expressed throughout the brain and body. However, the pathology of HD is characterized by early and dramatic destruction selectively of the striatum. We previously reported that the striatal-specific protein Rhes binds mHtt...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mealer, Robert G., Murray, Alexandra J., Shahani, Neelam, Subramaniam, Srinivasa, Snyder, Solomon H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916556/
https://ncbi.nlm.nih.gov/pubmed/24324270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536912
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