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Rhes travels from cell to cell and transports Huntington disease protein via TNT-like protrusion

Tunneling nanotubes (TNT) are thin, membranous, tunnel-like cell-to-cell connections, but the mechanisms underlying their biogenesis or functional role remains obscure. Here, we report, Rhes, a brain-enriched GTPase/SUMO E3-like protein, induces the biogenesis of TNT-like cellular protrusions, “Rhes...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Sharma, Manish, Subramaniam, Srinivasa
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548131/
https://ncbi.nlm.nih.gov/pubmed/31076452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807068
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