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The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle

Eukaryotic chromosome segregation relies upon specific connections from DNA to the microtubule-based spindle that forms at cell division. The chromosomal locus that directs this process is the centromere, where a structure called the kinetochore forms upon entry into mitosis. Recent crystallography...

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Publicat a:Open Biol
Autors principals: Kixmoeller, Kathryn, Allu, Praveen Kumar, Black, Ben E.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333888/
https://ncbi.nlm.nih.gov/pubmed/32516549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200051
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