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An epigenetic mark generated by the incorporation of CENP-A into centromeric nucleosomes

Mammalian centromeres are defined epigenetically. Although the physical nature of the epigenetic mark is unknown, nucleosomes in which CENP-A replaces histone H3 are at the foundation of centromeric chromatin. Hydrogen/deuterium exchange MS is now used to show that assembly into nucleosomes imposes...

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Detalhes bibliográficos
Main Authors: Black, Ben E., Brock, Melissa A., Bédard, Sabrina, Woods, Virgil L., Cleveland, Don W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829255/
https://ncbi.nlm.nih.gov/pubmed/17360341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700390104
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