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An epigenetic mark generated by the incorporation of CENP-A into centromeric nucleosomes
Mammalian centromeres are defined epigenetically. Although the physical nature of the epigenetic mark is unknown, nucleosomes in which CENP-A replaces histone H3 are at the foundation of centromeric chromatin. Hydrogen/deuterium exchange MS is now used to show that assembly into nucleosomes imposes...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1829255/ https://ncbi.nlm.nih.gov/pubmed/17360341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700390104 |
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