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The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle

Eukaryotic chromosome segregation relies upon specific connections from DNA to the microtubule-based spindle that forms at cell division. The chromosomal locus that directs this process is the centromere, where a structure called the kinetochore forms upon entry into mitosis. Recent crystallography...

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Bibliografiske detaljer
Udgivet i:Open Biol
Main Authors: Kixmoeller, Kathryn, Allu, Praveen Kumar, Black, Ben E.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333888/
https://ncbi.nlm.nih.gov/pubmed/32516549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200051
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