Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N

Accurate chromosome segregation requires the proper assembly of kinetochore proteins. A key step in this process is the recognition of the histone H3 variant CENP-A in the centromeric nucleosome by the kinetochore protein CENP-N. We report cryo–electron microscopy (cryo-EM), biophysical, biochemical...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Chittori, Sagar, Hong, Jingjun, Saunders, Hayden, Feng, Hanqiao, Ghirlando, Rodolfo, Kelly, Alexander E., Bai, Yawen, Subramaniam, Sriram
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292214/
https://ncbi.nlm.nih.gov/pubmed/29269420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar2781
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