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Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N

Centromeres are specialized chromosomal domains that direct kinetochore assembly during mitosis. CENP-A, a histone H3-variant present exclusively in centromeric nucleosomes, is thought to act as an epigenetic mark that specifies centromere identity. Here we identify the essential centromere protein...

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Main Authors: Carroll, Christopher W., Silva, Mariana C.C., Godek, Kristina M., Jansen, Lars E.T., Straight, Aaron F.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704923/
https://ncbi.nlm.nih.gov/pubmed/19543270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1899
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