CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere

Inheritance of each chromosome depends upon its centromere. A histone H3 variant, CENP-A, is essential for epigenetically marking centromere location. We find that CENP-A is quantitatively retained at the centromere upon which it is initially assembled. CENP-C binds to CENP-A nucleosomes and is a pr...

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Publicado en:Science
Main Authors: Falk, Samantha J., Guo, Lucie Y., Sekulic, Nikolina, Smoak, Evan M., Mani, Tomoyasu, Logsdon, Glennis A., Gupta, Kushol, Jansen, Lars E. T., Van Duyne, Gregory D., Vinogradov, Sergei A., Lampson, Michael A., Black, Ben E.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610723/
https://ncbi.nlm.nih.gov/pubmed/25954010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1259308
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