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CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere
Inheritance of each chromosome depends upon its centromere. A histone H3 variant, CENP-A, is essential for epigenetically marking centromere location. We find that CENP-A is quantitatively retained at the centromere upon which it is initially assembled. CENP-C binds to CENP-A nucleosomes and is a pr...
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| Pubblicato in: | Science |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610723/ https://ncbi.nlm.nih.gov/pubmed/25954010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1259308 |
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