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Long-term retention of CENP-A nucleosomes in mammalian oocytes underpins transgenerational inheritance of centromere identity

Centromeres control genetic inheritance by directing chromosome segregation but are not genetically encoded themselves. Rather, centromeres are defined by nucleosomes containing CENP-A, a histone H3 variant [1]. In cycling somatic cells, centromere identity is maintained by an established cell cycle...

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Vydáno v:Curr Biol
Hlavní autoři: Smoak, Evan M., Stein, Paula, Schultz, Richard M., Lampson, Michael A., Black, Ben E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846481/
https://ncbi.nlm.nih.gov/pubmed/27040782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.02.061
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