Long-term retention of CENP-A nucleosomes in mammalian oocytes underpins transgenerational inheritance of centromere identity

Centromeres control genetic inheritance by directing chromosome segregation but are not genetically encoded themselves. Rather, centromeres are defined by nucleosomes containing CENP-A, a histone H3 variant [1]. In cycling somatic cells, centromere identity is maintained by an established cell cycle...

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Bibliografiska uppgifter
I publikationen:Curr Biol
Huvudupphovsmän: Smoak, Evan M., Stein, Paula, Schultz, Richard M., Lampson, Michael A., Black, Ben E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846481/
https://ncbi.nlm.nih.gov/pubmed/27040782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.02.061
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