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Diabetes induces hepatocyte pyroptosis by promoting oxidative stress-mediated NLRP3 inflammasome activation during liver ischaemia and reperfusion injury

BACKGROUND: Although diabetes mellitus has been reported to aggravate liver ischaemia and reperfusion (IR) injury, the basic mechanism remains largely unknown. The object of the present study was to determine the role of oxidative stress and hepatocellular pyroptosis in liver IR injury in diabetic m...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Shi, Chengyu, Wang, Qi, Rao, Zhuqing, Shi, Yong, Wei, Song, Wang, Hao, Lu, Xu, Wang, Ping, Lu, Ling, Zhou, Haoming, Cheng, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333130/
https://ncbi.nlm.nih.gov/pubmed/32647664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-1839
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