Diabetes induces hepatocyte pyroptosis by promoting oxidative stress-mediated NLRP3 inflammasome activation during liver ischaemia and reperfusion injury

BACKGROUND: Although diabetes mellitus has been reported to aggravate liver ischaemia and reperfusion (IR) injury, the basic mechanism remains largely unknown. The object of the present study was to determine the role of oxidative stress and hepatocellular pyroptosis in liver IR injury in diabetic m...

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Vydáno v:Ann Transl Med
Hlavní autoři: Shi, Chengyu, Wang, Qi, Rao, Zhuqing, Shi, Yong, Wei, Song, Wang, Hao, Lu, Xu, Wang, Ping, Lu, Ling, Zhou, Haoming, Cheng, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333130/
https://ncbi.nlm.nih.gov/pubmed/32647664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-1839
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