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A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of MHAA4549A, a Monoclonal Antibody, plus Oseltamivir in Patients Hospitalized with Severe Influenza A Virus Infection

For patients hospitalized with severe influenza A virus infection, morbidity and mortality remain high. MHAA4549A, a human monoclonal antibody targeting the influenza A virus hemagglutinin stalk, has demonstrated pharmacological activity in animal studies and in a human influenza A challenge study....

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Lim, Jeremy J., Nilsson, Anna C., Silverman, Michael, Assy, Nimer, Kulkarni, Priya, McBride, Jacqueline M., Deng, Rong, Li, Chloe, Yang, Xiaoying, Nguyen, Allen, Horn, Priscilla, Maia, Mauricio, Castro, Aide, Peck, Melicent C., Galanter, Joshua, Chu, Tom, Newton, Elizabeth M., Tavel, Jorge A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318030/
https://ncbi.nlm.nih.gov/pubmed/32393496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00352-20
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